美国的比较. 个人和家庭计划药物保险对过度活跃的膀
Neha G Gaddam1, Megan B Wallace2, Alexis A Dieter3
1From the MedStar Washington Hospital Center/Georgetown University.
Urogynecology (Philadelphia, Pa.)
|March 14, 2024
概括
过活性膀 (OAB) 药物的保险覆盖范围各不相同,首选的治疗方法往往比具有认知风险的药物更糟糕. 需要扩大对更安全的OAB药物的覆盖范围.
科学领域:
- 药物经济学 药物经济学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗保险 医疗保险 医疗保险
背景情况:
- 对过度活跃膀 (OAB) 的抗胆固醇药物与显著的长期认知风险有关.
- 对OAB治疗的保险覆盖的变化,包括抗胆固醇药和β-3激动剂,可能会阻碍个性化的患者护理.
研究的目的:
- 为了评估医疗保险覆盖范围,通常处方过活性膀 (OAB) 药物.
- 为了比较首选的OAB药物和具有较高认知障碍风险的药物之间的保险覆盖范围.
主要方法:
- 对美国顶级医疗保险公司的保险表单进行了横截面分析.
- 评估了七种OAB药物的覆盖层,比较非偏好的 (oxybutynin,solifenacin) 和偏好的 (trospium,mirabegron,vibegron) 药物.
- 计算了覆盖率得分,以量化和比较表单可访问性.
主要成果:
- 分析包括41个州的2,780个保险计划.
- 与非首选选项相比,首选的OAB药物通常具有更高的配方级别和更差的覆盖率 (P < 0.001).
- 各保险公司的覆盖范围一致性各不相同,特别是在膀特异性抗胆固醇药和延长释放配方方面.
结论:
- 尽管与抗胆固醇药物相关的认知风险已知,但β-3激动剂往往更昂贵,保险覆盖率更低.
- 扩大对首选OAB药物的保险覆盖面对促进减轻认知风险的治疗选择至关重要.
相关概念视频
Drugs for Treatment of Diarrhea-Predominant IBS
167
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
167
Bioequivalence: Overview
1.0K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
1.0K
Drugs for Treatment of Constipation-Predominant IBS
162
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
162
Renal Drug Clearance: Comparison Between Renal Excretion Methods
134
Renal clearance is a critical parameter encompassing kidney filtration, secretion, and reabsorption processes. It is calculated using a specific equation to determine the rate at which the kidneys clear a drug.
Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
134
Drug Dosage Regimen: Overview
3.5K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.5K
Prescription, Nonprescription and Orphan Drugs
726
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
726


