利多卡因注射用于息性瘤护理的肌关节疼痛综合征:一项随机临床研究
Laís Araujo Dos Santos-Vilar1, Isabella Fioravante Freitas-Passos1, Beatriz Menin Rossi1
1Department of Internal Medicine, Medicine and Rehabilitation of the Locomotor Apparatus, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
1%的利多卡因注射有效地减少了接受息治疗的晚期癌症患者的肌肌带疼痛综合征 (MPS) 疼痛. 这种治疗也减少了对止痛药的需求,改善了患者的幸福感.
科学领域:
- 在瘤学瘤学.
- 疼痛管理 疼痛管理
- 抚慰性护理是一种缓解性护理.
背景情况:
- 身体疼痛是晚期癌症患者的一个重要问题.
- 肌肌关节疼痛综合征 (MPS) 是缓解护理 (PC) 癌症患者常见的疼痛组成部分.
- 在这种人群中治疗MPS疼痛时,缺乏1%的利多卡因注射的证据.
研究的目的:
- 评估1%的利多卡因注射对MPS减轻癌症患者在息治疗中的疼痛的疗效.
- 评估利多卡因注射对疼痛强度和药物需求的影响.
主要方法:
- 单盲随机临床试验涉及30名末期癌症和MPS (VAS ≥5) 的患者 (≥50岁).
- 干预组接受了1%利多卡因的触发点 (TP) 注射;对照组没有接受TP注射.
- 在干预前和后 (72小时) 评估疼痛强度 (VAS),压力值 (高压计) 和药物使用.
主要成果:
- 利多卡因组显示,可参考疼痛强度显著降低 (p < 0.001) 和压力值增加 (p = 0.007).
- 干预组中较高频率的患者减少了止痛药剂量/类 (p = 0.011).
- 在对照组中没有观察到任何显著的变化.
结论:
- 在触发点注射百分之一的利多卡因是一种有效的治疗方法,可以减少肌肌关节疼痛综合征的疼痛.
- 这种干预方法为治疗晚期癌症患者的疼痛提供了一个有希望的方法.
- 利多卡因注射可能有助于减少这种患者群体对止痛药物的依赖.
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