相关实验视频
Updated: Jun 30, 2025

06:35
Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
4.1K
在急性胰腺炎后,胰腺外分功能发生变化
Joseph Bejjani1, Mitchell L Ramsey1, Peter J Lee1
1Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
概括
外分胰腺功能障碍 (EPD) 可能发生在急性胰腺炎 (AP) 后,甚至轻微的病例. 了解其原因和管理对于患者健康至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 胰腺学 胰腺学
- 内部医学 内部医学
背景情况:
- 外分胰腺功能障碍 (EPD) 是胰腺疾病的吸收不良并发症.
- EPD可以引起浮,腹,减肥和代谢性骨病等症状.
- 在急性胰腺炎 (AP) 后,EPD越来越多地被认可,包括轻度病例.
研究的目的:
- 讨论EPD的流行病学,病理生理学和AP后EPD的临床管理.
- 突出了解和治疗EPD后AP的关键知识差距.
主要方法:
- 文献综述和对AP后EPD当前研究的综合.
- 分析影响EPD后AP发展的因素,如细胞破坏和炎症.
- 讨论AP后持续的结构变化.
主要成果:
- 在AP后EPD的风险与初始发作期间胰腺损伤的严重程度有关.
- 在AP后持续存在的结构异常有助于EPD的发展.
- EPD可以表现为一系列胃肠道和代谢症状.
结论:
- 晚期胰腺炎是急性胰腺炎的重大并发症,需要进一步调查.
- 为了有效的临床管理,需要对EPD病理生理学有更好的理解.
- 解决EPD后AP的知识差距对于改善患者的治疗结果至关重要.
相关概念视频
Chronic Pancreatitis I: Introduction
87
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
87
Acute Pancreatitis I: Introduction
357
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
357
Acute Pancreatitis II: Clinical Manifestations and Management
122
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
122
Chronic Pancreatitis II: Collaborative Care
86
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
86
Cells and Secretions of the Pancreas
2.2K
The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
2.2K
Pancreatic Juice and Secretion
799
Pancreatic juice is a clear fluid produced by the pancreas, containing water, salts, sodium bicarbonate, and enzymes vital for digestion in the small intestine. It helps break down large molecules, facilitating nutrient absorption.
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
799

