透皮专利孔圆形关闭:中风和超越
Sandeep Randhawa1, Jawahar L Mehta1, Gaurav Dhar1
1Division of Cardiology, The University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Current cardiology reviews
|March 14, 2024
概括
现在,对于60岁以下的密码性中风患者,通过皮肤关闭专利卵膜 (PFO) 已经优于单独的医疗治疗. 这种FDA批准的程序为预防复发性中风提供了一种新的治疗选择.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 医疗器械 医疗器械
背景情况:
- 缺血性中风在美国每年影响超过75万,其中40%发生在60岁以下的人群中.
- 密码性中风占所有缺血性中风的25%,尽管进行了彻底的调查,但缺乏可识别的原因.
- 专利Foramen Ovale (PFO) 通过矛盾的栓塞或血小板激活与中风引起有关.
研究的目的:
- 审查PFO的诊断方法.
- 探索PFO相关中风的假设机制.
- 总结支持PFO关闭的证据,并讨论患者选择,程序方面和并发症.
主要方法:
- 对PFO诊断和中风因果关系的现有文献的审查.
- 对临床试验数据的分析,将PFO关闭与医学治疗进行比较.
- 讨论穿皮关闭技术和结果.
主要成果:
- 虽然最初的PFO关闭试验得不到结论,但长期随访和最近的研究显示其优于单独的医学治疗.
- 最近针对60岁以下的密码性中风患者的试验表明,穿皮PFO闭合具有显著的益处.
- 这些发现导致FDA批准了穿皮PFO关闭装置.
结论:
- 皮肤穿PFO关闭是优越的治疗选择,相比单独治疗医疗选择的密码性中风患者.
- 患者选择,程序考虑和对潜在并发症的认识对于成功关闭PFO至关重要.
- 本综述为管理PFO和密码性中风患者的临床医生提供了全面的概述.
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