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Updated: Jun 30, 2025

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines

Published on: June 23, 2019

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设计,合成,抗瘤活动评估和模拟一些2-阿米诺皮拉衍生物的分子动力学

Hangrui Cui1, Ruifeng Zhang1, Xin Xiong1

  • 1Institute of Advanced Pharmaceutical Technology, Department of Pharmacy, College of Medicine, Wuhan University of Science and Technology, Wuhan, 430081, China.

Current computer-aided drug design
|March 14, 2024
PubMed
概括

研究人员合成了新型的2-aminopyrazine衍生物,确定了化合物3e作为一种强大的抗瘤剂. 这种化合物有效地抑制了癌细胞的生长,并诱导了亡,因此需要进一步研究药物开发.

关键词:
这是一种2-aminopyrazine.这是一种SHP2抑制剂.这是一种抗瘤药物.分子对接的分子对接.分子动力学模拟模拟综合合成是一种合成.

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