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身体质量指数和年轻女性癌症风险
Pigi Dikaiou1,2,3, Jon Edqvist4,5, Jesper Lagergren6,7
1Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. pigi.dikaiou@gu.se.
Scientific reports
|March 15, 2024
概括
年轻女性的体重指数 (BMI) 较高与患几个与肥胖有关的癌症的风险较高有关. 这包括增加癌症相关死亡的可能性,突出显著的公共卫生问题.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 身体质量指数 (BMI) 与年轻女性癌症风险之间的关系尚未得到充分证实.
- 肥胖是一个日益严重的全球健康问题,已知与各种癌症有关.
研究的目的:
- 调查BMI与与肥胖有关的癌症,乳腺癌,所有癌症和年轻女性癌症相关死亡的风险之间的联系.
- 量化特定癌症的风险增加与上升的BMI在这个人口.
主要方法:
- 从1982年至2014年,利用了瑞典基于人口的登记册 (医疗出生,患者,死亡原因).
- 包括1,386,725名年龄在18-45岁的女性,平均随访时间为16.3年.
- 分析了与BMI类别有关的癌症发病率和与癌症相关的死亡.
主要成果:
- 较高的BMI显示出与发生的卵巢癌,结肠癌,子宫内膜癌,胰腺癌,直肠癌,胆囊癌,食道癌和细胞癌的线性正相关性.
- 具体来说,BMI ≥30的女性与BMI 22.5-<25的女性相比,子宫内膜 (2.33) 和卵巢 (1.48) 癌症的危险比率明显增加.
- 体重指数升高也与肥胖相关的癌症死亡风险增加有关.
结论:
- 年轻女性的BMI升高与患多种与肥胖有关的癌症的风险增加有线相关.
- 这些发现强调了年轻女性体重管理的重要性,以减少长期癌症风险和死亡率.
- 这项研究提供了关于BMI对大量年轻女性癌症风险的影响的关键证据.
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