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Updated: Jun 30, 2025

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巨细胞的过敏脱粒需要调动炎症组分的炎症组分

Andrea Mencarelli1,2, Pradeep Bist1, Hae Woong Choi3

  • 1Program in Emerging Infectious Diseases, Duke-National University of Singapore, Singapore, Singapore.

Nature immunology
|March 15, 2024
PubMed
概括

炎症体蛋白NLRP3和ASC通过形成"粒体体"复合体来调解杆细胞脱粒和过敏反应. 这种复合体对于抗原触发的巨细胞脱粒和互白素-1β释放至关重要,导致严重的炎症.

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