美国成年人睡眠时间和表型年龄之间的反转U形关系:基于人口的研究
Yanwei You1,2,3, Yuquan Chen4, Ruidong Liu1,5
1Division of Sports Science and Physical Education, Tsinghua University, Beijing, 100084, China.
Scientific reports
|March 15, 2024
概括
短时间和长时间的睡眠时间都与表型年龄的增加有关,这表明了反转的U形关系. 定期炼可能对长时间睡觉的人有好处,但对健康老龄化的短时间睡觉的人没有好处.
科学领域:
- 老年学是一门学科.
- 睡眠科学 睡眠科学
- 生物标志物 生物标志物
背景情况:
- 睡眠是健康衰老的关键,可修改的行为.
- 现型年龄,一个基于生物标志物的指数,为生物衰老提供了一种新的衡量标准.
- 了解睡眠对衰老的影响对于公共卫生干预至关重要.
研究的目的:
- 为了确定美国成年人睡眠时间的趋势.
- 调查睡眠时间与表型年龄之间的关联.
- 探索运动在睡眠时间与表型年龄关系中的适度作用.
主要方法:
- 利用了来自美国13569名成年人的国家健康和营养检查调查 (NHANES) 的数据.
- 使用生物标志物计算表型年龄,并通过自我报告和采访分析睡眠时间.
- 采用加权多变量线性回归和受限制的立方支线模型,并进行子组分析.
主要成果:
- 自2015-2016年以来,睡眠时间不足的趋势一直在下降.
- 极短的睡眠和长时间的睡眠都与更高的表型年龄有关.
- 睡眠时间和表型年龄之间存在一个反转的U形关系;运动对长时间睡觉的人有益,但对短时间睡觉的人不利.
结论:
- 睡眠持续时间显著影响生物衰老,偏离最佳持续时间与加速衰老有关.
- 运动可能会减轻长时间睡觉的人的衰老影响,但不是短时间睡觉的人.
- 研究结果提供了关于促进健康衰老的睡眠相关干预措施的见解.
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