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Updated: Jun 30, 2025

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
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一种基于昆素的衍生物表现出强烈和选择性的抗癌活性,通过Topo II抑制诱导PC-3细胞的细胞亡

Mayada E G Elsakka1, Mohamed M Tawfik2, Lamiaa A A Barakat1

  • 1Chemistry Department, Faculty of Science, Port Said University, Port Said, Egypt.

Journal of biomolecular structure & dynamics
|March 15, 2024
PubMed
概括

昆素化合物III和IV通过诱导亡和抑制多酶II表现出强烈的抗前列腺癌活性. 化合物IV在体内显著减少瘤,毒性最小,突出其治疗潜力.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.第二类II抑制的抑制.前列腺癌是前列腺癌.昆素 (quinoxaline) 是一种素.

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