全球纵向菌株是否可以在康复的COVID-19患者中评估无症状的微妙左心室功能障碍?
Hazem Mansour1, Aly Osama Abdelhady1, Walaa Adel Abdel Reheim1
1Department of Cardiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Journal of cardiovascular echography
|March 15, 2024
概括
轻微的左心室 (LV) 功能障碍可能在轻微的COVID-19感染后持续存在,即使射出分数正常. 全球纵向菌株 (GLS) 在康复的患者中检测到这种亚临床心脏问题.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 冠状病毒疾病2019 (COVID-19) 可能导致多系统炎症,可能影响心脏功能.
- 虽然往往保留,左心室 (LV) 功能可能会在COVID-19后表现出微妙的损害.
- 与COVID-19相关的细胞因子风暴与心脏损伤有关.
研究的目的:
- 在COVID-19幸存者中调查微妙的左心室 (LV) 功能障碍.
- 使用全球纵向应变 (GLS) 作为LV功能障碍的敏感标志物.
- 评估最近从轻度至中度COVID-19中恢复过来的患者的心脏功能.
主要方法:
- 一个单一中心的观察性研究包括90名稳定患者,这些患者患有轻度至中度的COVID-19.
- 在所有参与者身上都进行了胸前回声心脏成像.
- 全球纵向应变 (GLS) 被测量以评估LV功能.
主要成果:
- 所有患者都表现出正常的LV尺寸和射出分数.
- 很大一部分 (33.3%) 显示出亚临床 LV 功能障碍,以减少 GLS 表示.
- 降低的GLS与升的托洛和C反应蛋白水平有显著的相关性.
结论:
- 轻度至中度的COVID-19感染可能导致亚临床左心室 (LV) 功能障碍.
- 降低全球纵向应变 (GLS) 是这种COVID-19后心脏变化的关键指标.
- 使用GLS早期检测LV功能障碍可能对管理心血管后果至关重要.
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