玻尿酸与重症患者的连续肠道养相比:系统审查和元分析
Ahmed M Abdelbaky1, Wael G Elmasry1, Ahmed H Awad1
1Intensive Care Unit, Rashid Hospital - Dubai Health, Dubai, ARE.
Cureus
|March 15, 2024
概括
这一系统性审查发现,在重症患者中,玻尿酸和连续肠道养之间没有显著的差异. 虽然结果相似,但持续养显示出较低死亡率的趋势,这需要进一步调查.
科学领域:
- 关键护理医学 关键护理医学
- 营养支持 营养支持
- 基于证据的实践.
背景情况:
- 肠道食对于重症患者至关重要.
- 最优的方法,玻尿酸与连续养,是有争议的.
- 需要最近的证据来指导临床实践.
研究的目的:
- 系统地审查和元分析随机对照试验,比较玻尿酸和连续肠道养.
- 为了评估临床结果和临床死亡率在接受不同肠道养方法的重症患者.
主要方法:
- 在主要数据库 (PubMed,CINAHL,Web of Science,Scopus,Google Scholar) 进行全面的文献搜索,寻找过去五年内发表的研究.
- 包括9项随机对照试验 (RCT),涉及863名重症患者.
- 偏差风险评估和临床结果的元分析,包括胃肠道耐受性,吸收和死亡率.
主要成果:
- 对于腹,便秘,吐,膨胀,吸血或胃残留体积,没有观察到玻尿酸和连续肠道养之间的统计学上显著差异.
- 两种养方法之间,重症监护室 (ICU) 和医院死亡率,以及ICU和医院住院时间,没有显著差异.
- 死亡率结果 (ICU和医院) 接近统计学意义,有利于持续的肠道养.
结论:
- 玻尿酸和连续肠道养在重症患者中显示了可比的临床结果.
- 持续的肠道养可能会在降低死亡率方面提供轻微的,但在统计学上并不显著的优势.
- 建议进行进一步的研究,以确认连续养对死亡率的潜在益处.
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