在脊椎压缩骨折患者中,片治疗对阿片类药物的使用的影响
Ben Silverman1, Frances Shofer2, Kirk Bonner1
1Physical Medicine and Rehabilitation, Hospital of the University of Pennsylvania, Philadelphia, USA.
Cureus
|March 15, 2024
概括
脊柱整形 (KP) 可能减少阿片类药物使用和脊柱压缩骨折 (VCF) 患者的疼痛. 这项研究发现,在未使用过阿片类药物的患者中,手术后阿片类药物处方和疼痛得分下降.
科学领域:
- 整形外科 整形外科 整形外科
- 疼痛管理 疼痛管理
- 神经外科 神经外科
背景情况:
- 脊椎压缩骨折 (VCF) 是导致疼痛和残疾的常见原因.
- 类阿片类止痛药经常被处方用于与VCF相关的疼痛.
- 囊整形 (KP) 是一种微创手术,用于治疗VCFs.
研究的目的:
- 评估手术前期与手术后90天的阿片类药物消耗.
- 评估VCF患者在KP后疼痛评分的变化.
主要方法:
- 对27名患者 (50-85岁) 的回顾性分析,他们接受了VCFs的KP.
- 对比了阿片类药物的使用 (每天的吗啡百万等值,阿片类药物的日数,MME总量) 和数值评分表 (NRS) 疼痛评分.
- 排除标准包括先前的阿片类药物使用,恶性瘤或其他并发手术.
主要成果:
- 在KP后,每天处方的MMEs显著减少 (中位数差异为17.7,p=.0009),阿片类药物日 (11.0,p=.0004) 和总MMEs (232.5,p<.0001) 观察到.
- 无论是先前使用过阿片类药物的组还是先前使用过阿片类药物的组,都显示了NRS疼痛评分的显著下降 (p<.0001).
结论:
- 囊整形 (KP) 可能导致VCF患者的阿片类药物利用率和疼痛水平降低.
- 结果表明,KP可能是对VCF患者疼痛管理的有益干预措施.
- 进一步研究将KP与保守治疗方法进行比较是有必要的,以证实这些结果.
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