头部摇摆模式可以区分患有梅尼尔病的患者与外围前庭功能下降?
Jennifer L Kelly1,2, Maura Cosetti1,2, Anat V Lubetzky3
1Ear Institute, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, United States.
Frontiers in neurology
|March 15, 2024
概括
头部安装显示器 (HMD) 技术通过测量头部摆动来有效地识别前庭缺陷功能 (VH). 然而,这项试点研究发现头部摇摆并没有显著区分Meniere.
科学领域:
- 静脉系统疾病 静脉系统疾病
- 姿势控制评估评估 姿势控制评估
- 装在头部的显示器 (HMD) 技术
背景情况:
- 梅尼尔氏病 (Meniere's disease,简称MD) 呈现出偶发性,听力损失和耳,由于症状变化,造成诊断挑战.
- 客观诊断测试对MD有价值,而HMD的头部动力学显示出对前置功能障碍的敏感性.
- 这项研究探讨了HMD衍生的头部摆动,以区分MD,前置功能缺陷 (VH) 和健康对照.
研究的目的:
- 调查使用HMD进行头部摇摆测量的实用性,以区分患有Meniere病 (MD),前庭功能缺陷 (VH) 和健康个体的患者.
- 在不同的视觉条件下,评估头部摇摆参数对前庭缺陷的敏感性.
主要方法:
- 80名成年人 (30名对照组,32名VH,18名MD) 使用HTC Vive Pro Eye HMD进行了姿势控制评估.
- 在静态和动态视觉负载条件下,记录了前后,中侧,俯仰,偏斜和滚动方向的头部摆动.
- 头部摇摆的根平均平方速度 (VRMS) 在20秒和60秒间隔内得到量化.
主要成果:
- 患有VH的参与者在静态和动态视觉条件下,在多个方向的头部VRMS显著高于对照组.
- 在MD患者和对照组或VH组之间没有观察到头部摇摆的显著差异.
- 患有多发性硬化症的患者表现出头部摇摆的高变化,平均值在对照组和VH参与者之间有所下降.
结论:
- 用HMD测量的头部摆动对前庭功能缺陷 (VH) 很敏感,并显示出作为体位控制中感官集成的临床结果测量潜力.
- 需要进一步研究更大的样本大小,并考虑症状严重程度,以确定HMD衍生的头部摆动是否可以可靠地诊断Meniere病 (MD).
- 在不同测试持续时间的可移植性和一致的发现表明,临床内HMD评估的可行性.
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