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Updated: Jun 30, 2025

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SKAP2在CD11b/CD18的下游作用,调节中性粒细胞效应体的功能

Panagiota Bouti1, Bart J A M Klein1, Paul J H Verkuijlen1

  • 1Department of Molecular Hematology Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.

Frontiers in immunology
|March 15, 2024
PubMed
概括

与Src酶相关的蛋白2 (SKAP2) 在中性粒细胞功能中起着双重作用. 它调节了CD11b/CD18介导的actin动态和集群,影响了效应因子的功能,如细胞化和细胞毒性.

关键词:
在CD11b/CD18整体中.Src 激酶相关的蛋白2 (SKAP2)粘附性 粘附性 粘附性 粘附性抗体依赖的细胞细胞毒性 (ADCC)丝状的行为.中性粒细胞中性粒细胞.发酵细胞的形成 发酵细胞的形成

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