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Updated: Jun 30, 2025

Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing ChIP-seq
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IFIH1-A946T风险变体以性别依赖的方式促进糖尿病

Amanda J Stock1, Pierina Gonzalez Paredes1, Luciana Previato de Almeida1

  • 1Oklahoma Medical Research Foundation, Arthritis & Clinical Immunology, Oklahoma City, OK, United States.

Frontiers in immunology
|March 15, 2024
PubMed
概括

在IFIH1中,一种特定的基因变异 (rs1990760) 通过增强免疫反应,增加了1型糖尿病 (T1D) 的风险. 这项研究表明,这种变异改变了免疫细胞的功能,在小鼠模型中促进了T1D的发展.

关键词:
IFIH1 的意思是MDA5 MDA5 MDA5 是一个简单的数字.在T细胞,T细胞.糖尿病 糖尿病患者 糖尿病患者胰岛素炎是一种炎症.第一种类型的干扰子干扰子.

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