脊椎病:关于病理生理学,分类和管理的最新情况
Sophie Williams1, Ingvar Bjarnason2, Bu'Hussain Hayee2
1Department of Colorectal Surgery, King's College Hospital, London, UK.
Frontline gastroenterology
|March 15, 2024
概括
脊椎病影响了许多人,年轻人中发病率越来越高. 本综述审查了关于其原因,危险因素和治疗的最新研究.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 流行病学 流行病学
背景情况:
- 结肠异瘤在80岁时影响70%的西方成年人,在年轻人群中发病率上升.
- 椎病 (DD) 影响10-25%的人,导致急性椎炎和潜在的并发症,如,出血或穿孔.
- DD的并发症对全球发病率和死亡率做出了重大贡献,同时也承担了管理慢性症状的负担.
研究的目的:
- 审查目前对分歧性疾病 (DD) 病理生理学的理解.
- 探索DD的不断变化的风险因素,分类系统和治疗策略.
- 基于最近的科学证据,挑战围绕DD的传统概念.
主要方法:
- 对最近关于分歧性疾病的研究进行文献综述.
- 对包括饮食,结肠结构,运动性和遗传学在内的多因素贡献者的分析.
- 综合有关病理生理学,危险因素,分类和治疗的当前数据.
主要成果:
- DD的病理生理学是复杂的和多因素的,涉及饮食,结肠壁结构,运动性和遗传学.
- 关于DD的传统观点正受到新的研究发现的挑战.
- 由于DD的复杂性,很难建立有效的预防措施.
结论:
- 对DD的复杂病理生理学的全面了解对于开发有效的干预措施至关重要.
- 最近的进展需要重新评估DD的风险因素,分类和治疗方法.
- 需要进一步的研究,以应对 diverticular疾病日益增长的全球健康负担.
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