相关实验视频
Updated: Jul 9, 2026
09:03
Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
15.8K
丝和丝纤维启发的聚合物纳米材料的进展,用于药物输送
Marisa O Pacheco1, Lauren E Eccles1, Nickolas A Davies2
1Department of Chemical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL.
Frontiers in chemical engineering
|March 15, 2024
概括
基于丝的纳米材料为向药物和基因传递提供了生物相容和生物降解的解决方案. 它们的可调节性质和功能化潜力使它们成为各种治疗应用的前景.
科学领域:
- 生物材料科学 生物材料科学
- 纳米技术 纳米技术
- 药物输送系统 药物输送系统
背景情况:
- 基于聚合物的纳米材料正在彻底改变药物和基因传递.
- 自然衍生的聚合物提供生物降解性和生物吸收优势.
- 丝和以丝为灵感的聚合物具有吸引力,因为它们的生物相容性,可调性特性和功能化能力.
研究的目的:
- 审查丝和以丝为灵感的聚合物,用于制造纳米材料.
- 讨论基于丝的聚合物纳米材料的制造技术.
- 详细介绍这些纳米材料在药物输送到各种微环境中的应用.
主要方法:
- 在纳米材料制造中对丝和丝灵感的聚合物进行文献综述.
- 综合和功能化策略的分析.
- 在各种生物环境中检查药物输送应用.
主要成果:
- 确定用于纳米材料的丝和丝灵感聚合物的关键类别.
- 制造技术的概述,使可调节纳米材料设计成为可能.
- 证明基于丝的纳米材料在向药物输送中的潜力.
结论:
- 丝和以丝为灵感的聚合物是先进药物输送系统的多功能平台.
- 制造技术允许为特定应用量身定制纳米材料特性.
- 这些生物材料显示出在不同的微观环境中提供有针对性的有意义的承诺.
相关概念视频
01:16Drug Delivery: Overview
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...
01:24Site-Targeted Drug Delivery Systems: Polymeric Carriers
Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...