在非随机抽样的情况下,电子健康记录数据的偏差校正模型
Jiyu Kim1, Rebecca Anthopolos1, Judy Zhong1
1Department of Population Health, NYU Grossman School of Medicine, New York University, 180 Madison Ave, New York, NY 10016, United States.
Biometrics
|March 15, 2024
概括
电子健康记录 (EHR) 可能有选择偏差. 我们开发了一种使用健康的社会决定因素来纠正这种偏见的新方法,提高了公共卫生研究的准确性.
科学领域:
- 公共卫生 公共卫生
- 生物统计学 生物统计学
- 医疗信息学 医疗信息学
背景情况:
- 电子健康记录 (EHR) 为公共卫生研究提供了大量的患者数据.
- 在电子健康记录中包含非随机受试者引入了选择偏见,限制了研究的有效性.
- 现有的EHR数据往往缺乏用于偏差校正的关键共变量.
研究的目的:
- 开发和验证使用健康的社会决定因素对EHR数据进行偏差校正的方法.
- 解决基于EHR的公共卫生研究中纠正选择偏差的方法上的差距.
- 增强电子健康记录的实用性,以便准确地推断公共卫生.
主要方法:
- 建议的赫克曼型偏差校正模型,包括健康共变量的社会决定因素.
- 使用这些共变量,模拟EHR非随机抽样概率.
- 在不同环境下通过模拟验证了该方法.
主要成果:
- 在纠正关联系数和结果平均值的偏差方面表现出有效性.
- 成功地应用了该方法来估计纽约市EHR中的心血管疾病患病率.
- 展示了该方法对未观察到的选择因子进行校正的能力.
结论:
- 拟议的Heckman型偏差校正方法有效地解决了EHR数据中的选择偏差.
- 纳入健康的社会决定因素可以提高使用EHR的公共卫生研究的准确性.
- 这种方法提高了EHR数据的可靠性,用于流行病学研究和卫生政策.
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