NCI癌症研究数据共享:分享癌症关键数据的资源
Zhining Wang1, Tanja M Davidsen1, Gina R Kuffel2
1Center for Biomedical Informatics and Information Technology, NCI, Rockville, Maryland.
Cancer research
|March 15, 2024
概括
美国国家癌症研究所.
科学领域:
- 在瘤学瘤学.
- 生物信息学是一种生物信息学.
- 数据科学数据科学数据科学
背景情况:
- 国家癌症研究所 (NCI) 在2014年建立了癌症研究数据共享 (CRDC).
- CRDC是一个生态系统,旨在容纳各种数据集,包括基因组,蛋白质组,成像和临床数据.
- 主要目标是支持癌症研究,并促进NCI资助研究的数据共享.
研究的目的:
- 审查CRDC生态系统中的各种数据共享.
- 描述它们的独特和共同的特点,成就和挑战.
- 讨论可查找,可访问,可互操作,可重复使用 (FAIR) 原则的实施和促进数据共享,与NIH数据管理和共享政策保持一致.
主要方法:
- 审查现有的NCI数据共享:基因组数据共享 (GDC),蛋白质组数据共享 (PDC),综合犬类数据共享 (ICDC),癌症数据服务 (CDS),成像数据共享 (IDC) 和临床和翻译数据共享 (CTDC).
- 分析每个数据共享的独特和共享的特性,成就和挑战.
- 评估FAIR原则的实施和数据共享战略.
主要成果:
- 提供了六个NCI数据共享的详细描述.
- 审查强调了这些平台的独特能力和共同点.
- 讨论了管理和共享这些多样化的数据集所遇到的成就和挑战.
结论:
- CRDC数据共享提供了一个强大的基础设施,用于癌症研究数据.
- 这些公共资源正在积极实施FAIR原则,以提高数据的可发现性和可用性.
- 该CRDC支持NIH数据管理和共享政策,促进更广泛地获取NCI资助的研究数据.
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