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使用圆束CT和实时电影MRI评估和验证喉运动

Seok-Joo Chun¹, Jaeman Son^1,2,3, Seonghee Kang^1,2,3

¹Department of Radiation Oncology, Seoul National University Hospital, 101 Daehak-ro, 03080, Jongno-gu, Seoul, Korea (Republic of).

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]

|March 15, 2024

概括

这项研究使用范赫克公式确定了早期喉癌的规划目标体积 (PTV) 边缘,并通过实时MRI验证了它们. 吞显著影响声带运动,需要策略,以尽量减少在放射治疗期间.

科学领域:

辐射瘤学辐射瘤学
医疗成像医学成像

背景情况:

准确的目标体积划分对于有效的放射治疗至关重要.
器官运动,特别是在头部和部区域,对于精确的辐射输送具有挑战性.
范赫克公式是基于系统 (Σ) 和随机 (σ) 错误计算规划目标量 (PTV) 利的标准方法.

研究的目的:

用范赫克公式来评估早期喉癌的规划目标体积 (PTV) 边缘.
通过实时磁共振成像 (MRI) 验证计算的PTV边缘.

主要方法:

分析了来自17名早期喉癌患者的形光束计算机断层扫描 (CBCT) 数据,以评估器官运动和量化系统 (Σ) 和随机 (σ) 错误.
使用范赫克公式计算PTV利:2.5Σ + 0.7σ.
在四名健康的志愿者身上进行了实时的斜视影像核磁共振,以评估声带运动 (内部目标体积 - ITV) 以及其与PTV的重叠.

主要成果:

确定了早期喉癌患者的系统和随机错误的数量,从而计算出PTV边缘为1.8mm (左至右),2.2mm (前后) 和5.3mm (上至下).
实时MRI验证显示,平均体积重叠比率 (ITVPTV) /ITV在没有吞的情况下为0.92,吞时为0.77.
在MRI验证中,PTV边缘为3mm (AP) 和5mm (SI) 应用于声带.

结论:

使用CBCT (1.8毫米LR,2.2毫米AP,5.3毫米SI) 计算的PTV边际与实时电影MRI发现有很好的一致性.
在放射治疗期间吞可能会导致声带的显著移位,影响目标覆盖率.
尽量减少吞和相关运动的策略对于优化喉癌早期治疗中放射治疗精度至关重要.

关键词:

圆光束CT CT 的情况.淋巴结膜癌是什么? 淋巴结膜癌是什么在PTV保证金中,PTV保证金是什么辐射疗法辐射疗法查看射线射线视图声带声带的声音.

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