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Updated: Jun 30, 2025

Identification of Kinase-substrate Pairs Using High Throughput Screening
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Identification of Kinase-substrate Pairs Using High Throughput Screening

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在ATM激酶中非同义SNP的计算分析:结构见解,功能影响和抑制剂发现

Nagesh Kishan Panchal1, Poorva Samdani2, Tiasa Sengupta2

  • 1Department of Biotechnology, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, 632 014, India.

Molecular biotechnology
|March 15, 2024
PubMed
概括

这项研究分析了Ataxia telangiectasia-mutated (ATM) 突变,确定了五种引起疾病的变异. 计算分析揭示了ATM相关癌症的潜在治疗点,如Y2080D和C2770G.

关键词:
在ATM 中,ATM 基因酶AZD1390:AZD0156 这里是AZD0156分子对接是分子对接.分子动力学模拟模型分子建模分子建模奎尔丁 (Quercetin) 是一种青素.

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