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在B单元格中对近距离TLR信号的TRAF3调节

Tiffany K Ybarra1,2, Gail A Bishop1,2,3

  • 1Interdisciplinary Graduate Program in Immunology, University of Iowa, 285 Newton Road, Iowa City, IA 52242, United States.

Journal of leukocyte biology
|March 15, 2024
PubMed
概括

在B细胞中的收费类受体 (TLR) 信号由TRAF3调节,它抑制了早期信号事件. 缺少TRAF3增强了TLR介导的B细胞激活,揭示了它作为负调节者的作用.

关键词:
B 细胞 B 细胞 B 细胞与TNF受体相关的因子 (TRAF)收费类受体 (TLR) 是一种类型的受体.细胞信号传递是细胞的信号传递.抑制机制的抑制机制骨髓分化的初级响应基因 (88) (MyD88)脊髓氨酸激酶 (Syk) 的作用

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