在老年患者的激进胃切除术后,腹内感染的预测模型
Xiaohan Yu1, Wanyun Tang2, Chenglin Bai3
1General Surgery Department, Dandong Central Hospital, China Medical University, Dandong, Liaoning, China.
Medicine
|March 15, 2024
概括
这项研究确定了老年患者胃癌手术后腹内感染的关键风险因素. 一个开发的诺莫格拉姆模型准确地预测了感染风险,有助于预防策略.
科学领域:
- 在瘤学瘤学.
- 外科胃肠道外科手术
- 老年医学 老年医学
背景情况:
- 胃癌 (GC) 是癌症死亡的主要原因,特别是在老年人中.
- 激进胃切除术是GC的主要治愈治疗方法.
- 手术后的腹内感染显著恶化了胃切除术后患者的预后.
研究的目的:
- 在老年GC患者的激进胃切除术后识别腹腔内感染的危险因素.
- 开发和验证这些感染的预测模型.
主要方法:
- 对322名经过激进胃切除手术的老年GC患者进行了回顾性分析.
- 患者分为感染者 (n=27) 和非感染者 (n=295) 组.
- 使用培训和验证套件开发和内部验证一个名ogram风险预测模型.
主要成果:
- 手术后腹内感染的发生率为8.3%.
- 确定的独立风险因素包括体重指数,葡萄糖,血红蛋白,白蛋白,手术持续时间和出血量.
- 在训练和验证队伍中,名图表表显示出出色的预测性能.
结论:
- 一个经过验证的诺莫格拉姆模型有效地预测了老年患者胃切除术后的腹内感染风险.
- 这种工具可以帮助临床医生实施有针对性的预防措施.
- 降低感染率可以改善接受手术的老年GC患者的结果.
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