遵守NCCN关于评估和治疗固体瘤患者贫血的指南
Demetra Hypatia Hufnagel1,2, Lia Manfredi Bos3, Alaina Johnson Brown4
11Vanderbilt University School of Medicine, Nashville, TN.
Journal of the National Comprehensive Cancer Network : JNCCN
|March 15, 2024
概括
贫血在癌症患者中很普遍,但对其评估和治疗的NCCN指导方针的遵守率很低. 通过加强准则遵守,有机会改善癌症护理.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
背景情况:
- 国家综合癌症网络 (NCCN) 的指导方针建议对癌症患者进行贫血评估和治疗.
- 关于遵守这些建议的数据有限.
研究的目的:
- 为了评估符合NCCN指南的贫血评估和治疗在患者的固体瘤.
主要方法:
- 一项回顾性队列研究分析了2008年至2017年期间诊断出固体瘤的25 018名患者.
- 贫血被定义为血红蛋白≤11 g/dL,并使用CTCAE v5.0.0进行分级.
- 铁缺乏症和维生素缺乏症的评估是根据NCCN指南进行的.
主要成果:
- 44%的患者在诊断后6个月内患有贫血,其中43%患有中度贫血.
- 只有37%的贫血患者接受了评估,39%接受了治疗.
- 治疗率随着贫血严重程度的增加而增加,但对指南的总体遵守率很低.
结论:
- 患有固体瘤的患者中贫血很常见,但基于指导方针的评估和治疗并不常见.
- 显著需要改善在癌症护理中对贫血管理的NCCN指南的遵守.
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