马拉维急症护理外科病人的输血和死亡率:一种倾向匹配的分析
Selena J An1, Natasha Ngwira2, Dylane Davis3
1Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
The Journal of surgical research
|March 15, 2024
概括
在马拉维,接受输血手术的患者在住院死亡的风险更高. 这突出了与低资源环境中的输血需求相关的严重疾病.
科学领域:
- 全球健康 全球健康
- 外科手术的结果
- 输血医学 输血医学
背景情况:
- 关于撒哈拉以南非洲的输血相关结果的数据有限.
- 在马拉维,对输血手术患者的死亡率预测因子的鉴定至关重要.
研究的目的:
- 确定在马拉维接受输血的急性护理外科病症患者的死亡率预测因素.
- 为了比较输血和非输血手术患者在低资源环境中的结果.
主要方法:
- 进行了回顾性倾向匹配分析.
- 分析了卡穆祖中央医院 (2013-2021) 7395名急性护理外科病情患者的数据.
- 输血患者与未输血患者的结果进行了比较.
主要成果:
- 输血患者年龄较大,女性比例较高,更早呈现,血红蛋白水平较低.
- 输血患者的并发症率 (62%对33%) 和住院死亡率 (25.5%对12.8%) 较高.
- 在倾向匹配后,输血患者在住院死亡的几率是住院死亡的三倍 (OR 3.3,95% CI 2.3-4.8).
结论:
- 马拉维手术患者的输血需求与危急疾病有关.
- 在这种情况下,输血的手术患者面临着显著更高的住院死亡的可能性.
- 需要对低资源环境中的输血实践和结果进行进一步的调查.
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