结直肠癌负担评估 (ABCRC) 工具;一个有效性和可靠性研究
Britt J M Thomassen1, Merel L Kimman2, Anne M J Somers3
1Department of Surgery, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, the Netherlands; School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, P.O. Box 616, 6200 MD, Maastricht, the Netherlands.
概括
结直肠癌负担评估 (ABCRC) 工具是评估结直肠癌治疗后患者报告结果的有效和可靠措施. 该工具通过评估生活质量和功能结果来支持个性化后续护理.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
- 医疗保健服务研究 医疗服务研究
背景情况:
- 结肠直肠癌 (CRC) 随访越来越多地优先考虑与健康相关的生活质量 (HRQoL) 和功能结果.
- 结直肠癌负担评估 (ABCRC) 工具是为了测量这些以患者为中心的结果而开发的.
- 该ABCRC工具集成了通用和CRC特定的模块,以评估疾病负担和生活方式.
研究的目的:
- 为了评估ABCRC工具项目的构造有效性.
- 评估ABCRC工具用于测量患者结果的可靠性.
- 确定ABCRC工具是否适用于CRC后续的临床应用.
主要方法:
- 177名接受手术CRC治疗的随访患者完成了ABCRC工具和其他经过验证的患者报告结果测量 (PROM).
- 通过与现有PROM和子组比较的相关性分析来评估构造有效性.
- 通过两次使用ABCRC工具,隔8天,计算类内相关系数 (ICCs) 来评估可靠性.
主要成果:
- 大多数ABCRC工具项目显示预期的相关性与已建立PROM的域 (例如,EORTC QLQ-C30,QLQ-CR29),支持构造有效性 (p<0.05).
- 该工具展示了区分患者子组的能力.
- 大多数项目的高ICC值 (>0.70) 表明了良好的测试重试可靠性.
结论:
- 该ABCRC-工具是一个有效和可靠的工具,用于评估患者在结直肠癌护理的结果.
- 该工具适用于临床实施,以加强个性化的后续策略.
- 通过测量HRQoL和治疗后的功能状态,ABCRC工具促进了以患者为导向的护理.
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