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Updated: Jun 30, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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(IV) 类药物与大麻素诱导线粒体功能障碍,并协同增强抗瘤作用

Tangli Wei1, Lihua Chen1, Pengmin Shi2

  • 1Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan 650500, PR China.

Journal of inorganic biochemistry
|March 15, 2024
PubMed
概括

研究人员开发了新的 (IV) 预药物,将酸与大麻二醇结合起来,以对抗结直肠癌中的化疗耐药性. 这些前药有效地通过诱导线粒体功能障碍和DNA损伤来杀死癌细胞,同时抑制DNA修复机制.

关键词:
大麻二醇 (Cannabidiol) 是一种细胞亡是细胞的亡.细胞毒性活动的细胞毒性.线粒体功能障碍 线粒体功能障碍(IV) 复合物 (IV) 复合物有协同作用的协同作用.

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