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Updated: Jun 30, 2025

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ATF3-CBS信号轴协调结直肠癌中的铁和瘤发生

Junjia Liu1, Xinyi Lu1, Siyu Zeng1

  • 1State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, Engineering Research Centre of Molecular Diagnostics of the Ministry of Education, School of Life Sciences, Xiamen University, Xiamen, Fujian, 361102, China.

Redox biology
|March 15, 2024
PubMed
概括

激活转录因子3 (ATF3) 有助于结直肠癌细胞通过在低氨酸条件下调节氨酸β-合成酶 (CBS) 来抵抗铁亡. 阻止这种ATF3-CBS通路可能会改善基于铁的癌症治疗.

关键词:
在ATF3-CBS信号轴上.大肠直肠癌 (CRC) 是一种癌症.铁化是铁化的一种.线粒体三碳酸 (TCA) 循环中的三碳酸 (TCA)

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