代谢综合征和肥胖症患者的阿迪波涅丁和肌肉质量之间的关系
Daniel de Luis1, David Primo1, Olatz Izaola1
1Center of Investigation of Endocrinology and Nutrition, Department of Endocrinology and Investigation, Medicine School, Hospital Clinico Universitario, University of Valladolid, 47003 Valladolid, Spain.
Journal of diabetes and its complications
|March 15, 2024
概括
肥胖老年人具有代谢综合征的低骨肌肉质量与较低的阿迪波内克水平有关. 这项研究突出了脂素的作用.
科学领域:
- 内分泌学 在内分泌学.
- 老年病的医生 老年病的医生
- 肥胖问题研究研究
背景情况:
- 亚迪波尼克丁是一种关键的亚迪波金,具有抗炎性质.
- 肥胖和肉症与慢性炎症有关.
研究的目的:
- 研究60岁以上代谢综合征的肥胖患者的骨肌肉质量和阿迪波涅克丁水平之间的关系.
主要方法:
- 对651名患有代谢综合征的肥胖患者进行横截面研究.
- 利用生物电阻 (BIA) 进行身体组成分析.
- 收集人体测量,血压和生化数据,包括HOMA-IR.
主要成果:
- 较低的骨肌肉质量指数 (SMMi) 与较高的氨酸水平有关.
- 血清脂肪素与脂肪质量,无脂肪质量和骨肌肉质量负相关.
- 在调整后,阿迪波涅丁水平解释了SMMi18%的变化.
结论:
- 血清腺素水平与代谢综合征的肥胖老年人低骨肌肉质量负面相关.
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