稳定性和编程的连续释放 Lactobacillus plantarum 和在双层稳定 W1/O/W2 双乳液中封装的黄素: 作为保护性外的素的影响
Yijie Hua1, Zihao Wei1, Changhu Xue1
1State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, Qingdao 266404, China.
International journal of biological macromolecules
|March 15, 2024
概括
这项研究开发了一种新型的卵纤维/基于pectin的双层稳定双重乳液 (OP-BDE),用于联合封装Lactobacillus plantarum和黄素. OP-BDE显示了增强的益生菌稳定性和在胃肠道中编程顺序释放.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物技术是生物技术.
- 材料科学 材料科学 材料科学
背景情况:
- 传统的W1/O/W2双乳液缺乏向释放能力,限制了它们在功能性食品中的应用.
- 开发提高益生菌和黄素等生物活性化合物的稳定性和生物可用性的传递系统对于消费者健康至关重要.
研究的目的:
- 构建一种新的卵蛋白纤维/基于pectin的双层稳定双重乳液 (OP-BDE),用于同时输送 Lactobacillus plantarum 和黄素.
- 评估点涂层在各种压力条件下对Lactobacillus plantarum生存能力的保护作用.
- 评估OP-BDE对黄素光稳定性,脂解和生物可访问性的影响,并研究其编程序列释放特性.
主要方法:
- 使用卵胺纤维和pectin作为稳定剂构建OP-BDE,同时封装Lactobacillus plantarum和黄素.
- 在储存,巴氏杀菌,冷解和体外模拟消化条件下评估Lactobacillus plantarum的生存能力.
- 评估黄素的光稳定性和生物可访问性,以及体外胃肠道释放研究,以确定连续释放模式.
主要成果:
- 丁涂层显著提高了Lactobacillus plantarum对环境压力因素的耐受性.
- OP-BDE表现出改善的脂解和增强的保护黄素,增加其光稳定性和生物可访问性.
- 在体外研究证实了OP-BDE的编程顺序释放,将黄素输送到小肠,而Lactobacillus plantarum则输送到结肠.
结论:
- 据报道,OP-BDE是第一个具有编程顺序释放特性的联合输送乳液系统.
- 这种新的系统为益生菌提供了增强的稳定性和改善了黄素的输送,具有功能性食品开发的重大潜力.
- 这些发现为设计食品生产中生物活性化合物的先进联合交付系统提供了宝贵的见解.
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