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对早期侵袭性乳腺癌的轴心超声波
Karen Jiang1, Crystal Ma1, Yuwei Yang2
1Faculty of Medicine, University of British Columbia, 317-2194 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada.
American journal of surgery
|March 15, 2024
概括
在早期侵袭性乳腺癌患者中,消除1~2个阳性哨兵节点的手术前腔超声波 (AxUS) 可以降低腔淋巴结解剖 (ALND) 率,而不会增加重复手术.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 乳腺癌管理 乳腺癌管理
背景情况:
- 哨兵淋巴结活检 (SLNB) 相当于小淋巴结剖析 (ALND) 早期侵袭性乳腺癌的1-2个阳性节点.
- 手术前的侧超声波 (AxUS) 可能会高估结节转移,可能导致过度治疗.
研究的目的:
- 为了比较手术前和没有手术前AxUS的患者的手术率.
- 评估与早期乳腺癌手术前AxUS相关的实用性和过度治疗风险.
主要方法:
- 追溯的队列研究.
- 包括患有临床T1/T2乳腺瘤,临床结节阴性状态和下手术的患者.
- 在接受手术前Axus治疗的患者和没有接受手术的患者之间,ALND和重新手术率的比较.
主要成果:
- 手术前AxUS患者的ALND发病率明显较高 (5.6%对1.4%,p < 0.001).
- 在SLNB后的额外手术中,两组之间没有显著差异 (2.1%对2.3%,p = 0.77).
结论:
- 遗漏手术前的AXUS与侵袭性ALND手术的减少有关.
- 切除手术前的AXUS并没有提高随后的关骨重新手术的比率.
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