在慢性病中药物管理,以实现有效和安全的药物使用
Rasheeda K Hall1, Rümeyza Kazancıoğlu2, Teerawat Thanachayanont3
1Division of Nephrology, Department of Medicine, and Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.
Nature reviews. Nephrology
|March 16, 2024
概括
对于患有慢性病 (CKD) 的人来说,最佳的药物管理对于管理多种疾病和药物至关重要. 本综述提供了关于CKD患者安全有效药物使用的指导.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床药理学 临床药理学
- 公共卫生 公共卫生
背景情况:
- 患有慢性病 (CKD) 的患者经常患有多病症,需要多药.
- 功能障碍会改变药物的药理动力学和药理动力学,影响药物的风险和益处,通常没有完全理解.
- 有效的药物管理对于最大限度地提高CKD患者药物安全性和疗效至关重要.
研究的目的:
- 作为一个全面的资源,以实现在患有CKD的患者中最佳的药物管理.
- 概述在特定的CKD患者群体和情况中使用药物的特殊考虑.
- 解决药物获取不平等问题,并提出政策改进建议.
主要方法:
- 审查关于CKD药物管理的当前文献和临床指南.
- 药物管理流程的描述:调和,选择,剂量调整,监测和停止处方.
- 包括关于特殊人群 (怀孕,哺乳期,急性疾病,癌症) 和物质类型 (OTC,草药,补充剂) 的指导.
主要成果:
- 提供了针对CKD患者量身定制的药物管理的详细考虑.
- 强调以患者为中心的护理,教育,数字健康和跨学科合作的重要性.
- 解决药物获取方面的全球不平等问题,并提出政策干预措施.
结论:
- 最佳的药物管理需要对患有CKD的个体采取多方面的以患者为中心的方法.
- 对于在各种CKD相关情景和患者子组中使用药物需要专门的指导.
- 改善药物获取和促进负责任的使用是提高对所有患有CKD的人的护理的关键.
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