表面静脉血栓形成及其与恶性瘤的关系:一项前性观察性研究
Alejandro Díez-Vidal1, Javier Gómez López2, Pablo Rodríguez Fuertes2
1Department of Internal Medicine, La Paz University Hospital, Paseo Castellana 261, Madrid, 28046, Spain. alejandro.diez@salud.madrid.org.
Journal of thrombosis and thrombolysis
|March 16, 2024
概括
表面静脉血栓症 (SVT) 与癌症有关,在患有恶性瘤的患者中表现更严重. 复杂的SVT可以预测未来的癌症发展,强调需要进一步的研究.
科学领域:
- 血管医学 血管医学
- 在瘤学瘤学.
- 血栓形成研究研究
背景情况:
- 癌症和静脉血栓塞栓症之间的关系是已知的,但其对表面静脉血栓症 (SVT) 发生率和进展的具体影响尚不清楚.
- 表面静脉血栓症 (SVT) 是一种影响靠近皮肤表面的静脉的疾病,通常会引起不适和炎症.
研究的目的:
- 调查表面静脉血栓症 (SVT) 与恶性瘤之间的关联.
- 分析与癌症相关的风险因素,临床表现,疾病过程和SVT并发症.
主要方法:
- 一个单一中心的前性观察研究.
- 包括被诊断患有深静脉血栓症 (DVT) 或SVT的患者.
- 从2013年1月到2018年4月,在专门的静脉血栓塞栓症诊所收集数据.
主要成果:
- 在632名患者中,205人患有SVT,其中16.6%患有活跃的癌症.
- 活跃癌症与近端SVT,结点附近SVT,双边SVT和多个静脉卷入的风险增加有关.
- 没有癌症史的SVT患者在随访期间显示出新发癌症的风险增加,特别是复杂的SVT表现或随后的DVT/PE.
结论:
- 在癌症史和SVT的发展之间存在可能的联系.
- 在癌症患者中,SVT呈现更严重,复杂的SVT可能作为未来癌症的预测标志物.
- 不同的药理疗法之间没有观察到治疗结果的显著差异.
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