在中国的一个儿科重症监护病房中,静脉血栓栓塞的危险因素
Jintuo Zhou1, Yanting Zhu1, Ying Liu1
1Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, #18 Daoshan Road, Fuzhou, China.
Thrombosis journal
|March 16, 2024
概括
儿科静脉血栓塞栓症 (VTE) 影响0.19%的儿童,休克和败血症是显著的危险因素. 这项研究强调了在中国儿科中对VTE进行更多研究的必要性.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 血液学 血液学 血液学
- 流行病学 流行病学
背景情况:
- 在全球范围内,静脉血栓塞栓症 (VTE) 在重症儿童中的患病率不断上升.
- 在中国人群中,关于儿童VTE的流行病学数据有限.
- 需要对不同种族和地理群体进行研究.
研究的目的:
- 确定中国儿科VTE的患病率和风险因素.
- 分析与严重疾病儿童VTE相关的社会人口统计学和临床因素.
- 解决中国儿科人口中VTE研究的差距.
主要方法:
- 使用儿科重症监护 (PIC) 数据库 (2010-2018) 的回顾性队列研究.
- 通过SQL和pgAdmin4.4提取数据.
- 两变量分析 (基平方,学生的t测试) 和多变量逻辑回归.
主要成果:
- 这项研究包括12881名儿科患者;VTE发病率为0.19%.
- 最常见的静脉瘤位置:四肢深静脉血栓 (DVT) (n=18).
- 冲击 (aOR:6.77) 和败血症入院 (aOR:6.09) 是儿科VTE的重要危险因素.
结论:
- 在PIC数据库中,儿科VTE患病率为0.19%.
- 极端的深静脉血栓 (DVT) 是最常见的静脉动脉瘤位置.
- 冲击和败血症是与儿科VTE相关的统计学上显著的独立风险因素.
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