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Updated: Jul 9, 2026

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使用机器学习模型和体外验证方法预测细胞染色体P450介导的生物激活

Xin-Man Hu1, Yan-Yao Hou1, Xin-Ru Teng1

  • 1State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, 15 Yucai Road, Guilin, 541004, People's Republic of China.

Archives of toxicology
|March 16, 2024
PubMed
概括

机器学习模型准确地预测了P450介导的生物激活,这是药物毒性的关键因素. 这种方法有助于设计更安全的药物,并在临床环境中评估药物不良反应.

关键词:
生物活化 生物活化在体外验证验证.机器学习 机器学习在P450中,P450是什么?

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