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Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
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YTHDF1-CLOCK轴通过LLPS促进过敏气道炎症的致病性

Jing Wang1, Yao Zhou2, Meng Zhang2

  • 1Department of Pediatrics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Cell reports
|March 16, 2024
PubMed
概括

YTHDF1,一个关键的N6-甲基氨酸读者,通过增强CLOCK翻译和激活NLRP3炎症酶,驱动过敏气道炎症. 向YTHDF1可能为喘提供新的治疗策略.

关键词:
CP: 免疫学 免疫学科普:分子生物学这是一种N6-甲基氨酸.在 YTHDF1 的位置上.过敏的气道炎症 过敏的气道炎症液态-液态相隔离方法 液态相隔离方法翻译翻译翻译翻译翻译翻译

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