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多发性硬化症男性性功能障碍的特征和预测因素

Ivan Adamec¹, Tomislav Sambolić², Mihovil Santini²

¹University Hospital Center Zagreb, Department of Neurology, Referral Center for Autonomic Nervous System Disorders, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia.

Multiple sclerosis and related disorders

|March 16, 2024

概括

性功能障碍,包括勃起功能障碍 (ED) 和早泄 (PE),在患有多发性硬化症 (MS) 的男性中很常见. EDSS得分预测ED,而疾病持续时间预测PE.

科学领域:

神经学神经学
泌尿器科泌尿器科泌尿器科泌尿器科
性医学性医学性医学性医学

背景情况:

多发性硬化症 (MS) 可以显著影响男性的性健康.
勃起功能障碍 (ED) 和早泄 (PE) 是常见的,但在这个人群中没有充分研究.

研究的目的:

验证和文化适应男性性健康库存 (IIEF-5) 和早泄诊断工具 (PEDT).
为了比较患有MS的男性 (mwMS) 与健康对照 (HC) 的ED和PE的患病率和严重程度.
在mWMS中确定ED和PE严重程度的预测因素.

主要方法:

216个mWMS和37个HC完成了IIEF-5和PEDT.
114 mwMS还完成了修改的疲劳影响量表 (MFIS),贝克抑郁 inventory (BDI-2),复合自主系统得分-31 (COMPASS-31),和EQ-5D.

主要成果:

在IIEF-5和PEDT中,证明了令人满意的测试复试可靠性.
mwMS报告的IIEF-5得分低于HC (p=0.028).
在39.4%的mWMS中存在ED,而在HC中存在27.8% (p=0.198);PE在12.1%的确定的/7.8%的可能,而在5.6%的确定的/11.1%的可能 (p=0.496) 中存在PE.
扩展残疾状况尺度 (EDSS) 评分预测ED (Exp(B) =1.455,p=0.003),而克雷马斯特反射预测ED (Exp(B) =0.381,p=0.010).
疾病持续时间预测PE (Exp(B) =1.084,p=0.070).

结论:

性功能障碍在患有MS的男性中普遍存在.
勃起障碍和质反应是勃起障碍的预测因素.
疾病持续时间是mWMS中PE症状的预测因素.

关键词:

克里马斯特反射反应勃起功能障碍是因为勃起功能障碍.男人男人男人男人男人多发性硬化症是多发性硬化症.过早射精 (premature ejaculation) 是一种早泄症.性功能障碍性功能障碍性功能障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性障碍性

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