更新功能性大脑单元:远远超出Luria的洞察力
Jordi Peña-Casanova1, Gonzalo Sánchez-Benavides2, Jorge Sigg-Alonso3
1Integrative Pharmacology and Systems Neuroscience Research Group, Neuroscience Program, Hospital del Mar Medical Research Institute, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Autonomous University of Barcelona, Bellaterra, Barcelona, Spain; Test Barcelona Services, Teià, Barcelona, Spain.
概括
这次审查修订了Luria的版本.
科学领域:
- 神经科学是一个神经科学.
- 神经生物学 神经生物学 神经生物学
- 认知科学 认知科学
背景情况:
- 亚历山大·卢里亚 (Alexander Luria) 关于三个功能性大脑单元的模型是神经科学中的一个基本概念.
- 了解大脑组织需要将功能系统理论与植物遗传学和胚胎遗传学原理相结合.
- 现有的模型往往难以将基本需求与复杂的行为和分层的大脑结构相协调.
研究的目的:
- 审查和批判性地分析卢里亚的功能大脑单元模型.
- 根据遗传学,胚胎学和系统视角提出一个更新的大脑组织模型.
- 在两个综合复合体内划分五个功能单位.
主要方法:
- 审查现有关于功能系统理论,原生和胚胎生成的文献.
- 分析同居需要与复杂行为之间的关系.
- 整合多层次层次和分布式大脑组织原则.
主要成果:
- 大脑表现出多层次的层次和分布式组织,具有复杂的细胞系统相互作用.
- 遗传学,特别是基底和小脑的扩张,显著影响大脑的扩张.
- 一个新的模型提出了两个集成的综合体:原始-边缘和脑电-皮层,包括五个功能单元.
结论:
- 卢里亚的原始三方模型受到大脑组织原则的挑战.
- 提出的五个功能单元 (大脑干,边缘/准边缘,脑皮层-皮层,基底,小脑) 提供了一个更完整的视图.
- 功能性大脑组织是动态的,涉及超越严格解剖界限的重叠过程.
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