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Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...

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相关实验视频

Updated: Jul 13, 2026

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue
08:08

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

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聚合酶链反应负的加密球菌脑膜炎.

Kyle T O'Meara1, June L Chan2, Stacey Ceron2

  • 1Department of Pulmonary & Critical Care, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Diagnostic microbiology and infectious disease
|March 16, 2024
PubMed
概括

即使有负的BioFire FilmArray脑膜炎/脑炎面板,也可能发生菌脑膜炎. 自由的加密球菌抗原检测对于准确的诊断至关重要,特别是在HIV阴性个体中.

关键词:
这是一种加密球菌抗原.密码球菌脑膜炎是什么?这是Cryptococcus neoformans的新型.脑膜炎是一种脑膜炎.分子诊断学 分子诊断学聚合酶连锁反应的发生.

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Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control
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相关实验视频

Last Updated: Jul 13, 2026

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue
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科学领域:

  • 传染性疾病 传染性疾病
  • 神经学 神经学
  • 临床微生物学 临床微生物学

背景情况:

  • 亚急性头痛是一种常见的症状,需要及时诊断.
  • 加密球菌脑膜炎是一种严重的机会性感染,特别是在免疫受损的个体中.
  • 脑膜炎/脑炎的诊断面板旨在快速识别引起病原体.

研究的目的:

  • 为了突出一个加密球菌脑膜炎的病例被多重PCR面板遗漏.
  • 为了强调BioFire FilmArray脑膜炎/脑炎面板对加密球菌脑膜炎的局限性.
  • 倡导更广泛地使用加密球菌抗原测试.

主要方法:

  • 一个61岁的男性患有亚急性头痛的病例报告.
  • 对诊断测试的审查,包括BioFire FilmArray和加密球菌抗原测试.
  • 临床相关性和结果评估.

主要成果:

  • 该患者被诊断患有密码球菌性脑膜炎.
  • 在BioFire FilmArray脑膜炎/脑炎小组的结果是负的.
  • 加密球菌抗原测试证实了诊断.

结论:

  • 一个负的BioFire FilmArray面板并不排除加密球菌脑膜炎.
  • 自由地使用加密球菌抗原测试对于准确诊断至关重要.
  • 不管艾滋病毒状况如何,在患有不明原因脑膜炎症状的患者中考虑加密球菌脑膜炎.