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在拉巴特 (摩洛哥) 住院的儿童中爆发百日咳疫情
Redouane Mammar Bennai1, Amal Zouaki1, Ghizlane El Amin1
1Mohamed V University, Faculty of Medicine and Pharmacy, Rabat, Morocco; Ibn Sina University Hospital Center, Specialties Hospital, Central Laboratory of Virology, Rabat, Morocco.
Diagnostic microbiology and infectious disease
|March 16, 2024
概括
严重的百日咳疫情正在影响幼儿,大多数病例发生在3个月以下的婴儿中. 这项研究强调了2023年疫情期间的流行率和临床特征.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 循环性百日咳流行病对幼儿的影响不成比例.
- 百日咳仍然是一个重大的公共卫生问题,特别是在脆弱的婴儿群体中.
- 了解当前的疫情动态对于及时干预和预防策略至关重要.
研究的目的:
- 在拉巴特大学医院中心估计2023年爆发期间百日咳的流行率.
- 为了确定在此期间受到百日咳影响的主要年龄组.
- 在受影响的患者中描述百日咳的临床表现.
主要方法:
- 对2021年1月至2023年6月期间入院的患者进行了回顾性研究.
- 对有症状的患者进行多重呼吸道面板PCR测试,以检测呼吸道病原体.
- 对RT-PCR的分析证实了Bordetella spp. 的存在. 情况,包括物种识别 (B. pertussis和B. parapertussis).
主要成果:
- 从2022年12月开始,人们观察到 pertussis病例的急剧增加,包括85.4%的阳性样本.
- 大多数病例 (78.2%) 是3个月以下的婴儿.
- 常见的症状包括咳 (94.5%) 和呼吸障碍 (94.5%);在81.8%的确诊病例中发现了Bordetella pertussis DNA.
结论:
- 这项研究证实了严重的百日咳疫情,主要影响幼儿.
- 早期识别和管理对于减轻百日咳在这个脆弱人口群体中的影响至关重要.
- 调查结果强调需要持续的监测和疫苗接种努力,以控制百日咳疫情.
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