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Updated: Jun 30, 2025

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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设计一种 (R) - 选择性转氨酶,用于 (R) - 3 - 氨基醇的不对称合成

He Liu1, Shixi Wang1, Meng Xu1

  • 1State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, China.

Bioorganic chemistry
|March 16, 2024
PubMed
概括

工程化 (R) 选择性转氨酶显示了用于合成奇拉胺的增强的催化效率和稳定性. 这一突破改善了对具有挑战性的基质的酶接受,推动了药物发现.

关键词:
(R) 选择性氨基酸酶转酶.不对称的合成方法初始活动活动初始活动热稳定性 热稳定性

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