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在早产婴儿的斑点白质病变上:超声波诊断是否可行?
Philippe Quétin1, Nicolas Leboucq2, Charlotte Boyer2
1Service de Néonatalogie, Centre Hospitalier Henri Duffaut, Avignon, France.
概括
常规的头骨超声波 (cUS) 能够有效地检测早产婴儿的超声波结节性或点状白质病变 (HNPL),与MRI检测的病变具有很高的相似性,并可能具有更好的灵敏度.
科学领域:
- 新生儿神经病学 新生儿神经病学
- 儿科放射学 儿科放射学
- 神经成像是一种神经成像.
背景情况:
- 过早出生的婴儿面临白质脑损伤的风险.
- 头骨超声波 (cUS) 是新生儿科的一个常见的成像方法.
- 斑点白质病变 (PWML) 是早产婴儿的MRI上已知的发现.
研究的目的:
- 使用常规cUS.US观察早产婴儿的高结节或点白质病变 (HNPL).
- 在cUS上观察到的HNPL的特征.
- 将cUS检测到的HNPL与MRI检测到的PWML进行比较.
主要方法:
- 追溯观察单中心队列研究.
- 包括307名早产婴儿在怀孕33周之前出生.
- 分析了961次常规CUS扫描和43次MRI扫描.
主要成果:
- 307名婴儿中有63名 (20.5%) 患有脑损伤,其中453名HNPL被确定.
- HNPL通常数量众多,聚集,位于侧腔室附近,尺寸大于2毫米.
- cUS在14/21名婴儿中检测到HNPL,这些婴儿在MRI上也有PWML;7名婴儿在cUS上有HNPL,但在MRI上没有PWML.
结论:
- 常规cUS可以在早产婴儿中诊断HNPL.
- 在cUS上观察到的HNPL与MRI上观察到的PWML显著相似.
- cUS可能为检测这些病变提供更好的灵敏度,但在没有观察者间变异数据的情况下存在过度诊断的风险.
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