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选择性向Plasmodium falciparum Hsp90破坏了26S蛋白质组的作用

Christopher R Mansfield1, Baiyi Quan2, Michael E Chirgwin2

  • 1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, USA.

Cell chemical biology
|March 16, 2024
PubMed
概括

热冲击蛋白90 (Hsp90) 对于Plasmodium falciparum的蛋白质稳定性至关重要. 抑制PfHsp90显示出抗疟疾活性,并揭示其在蛋白酶体功能中的作用,将其确定为药物标.

关键词:
在 Hsp90 中,Hsp90 是流感病毒 (Plasmodium) 是一种流感病毒.化学蛋白质组学化学组学热冲击蛋白质 90 90 90 90 90 90 90 90 90 热冲击蛋白质是什么?热冲击蛋白质是什么?蛋白质酶体蛋白质组是什么蛋白质稳定症是一种蛋白质稳定症.

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