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Updated: Jun 30, 2025

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诺托金化物R1向PPAR-γ,以抑制肝星细胞激活,并改善肝纤维化

Cheng Guo1, Linying Lai2, Boyu Ma2

  • 1Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, China.

Experimental cell research
|March 16, 2024
PubMed
概括

诺托金化物R1 (NR1) 通过激活PPAR-γ和抑制TGF-β1/Smads信号传递,有效治疗肝纤维化. 这种化合物显示出作为一种新的肝纤维化治疗方法的前景.

关键词:
肝脏纤维化 肝脏纤维化诺托基因化物R1 是一种诺托基因化物在PPAR-γ中使用PPAR.在TGF-β1/Smads路径中.

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