对营养不良的不同工具在评估肝硬化患者中的有效性
Gokulapriya Ramachandran1, Biju Pottakkat1, Pazhanivel Mohan2
1Department of Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research, Dhanvantri Nagar, Puducherry 605006, India.
肝移植候选人中营养不良非常普遍,低中臂周长和手握强度是常见的. 早期营养评估对于改善慢性肝病患者的治疗结果至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 营养科学 营养科学
- 移植医学 移植医学
背景情况:
- 肝硬化严重影响营养状况.
- 肝移植候选人经常出现营养不良.
- 传统的营养评估工具被用来评估这一群体.
研究的目的:
- 为了确定在等待肝移植的肝硬化患者中营养不良的患病率.
- 在这个群体中评估各种营养评估方法的有用性.
主要方法:
- 一项涉及215名肝硬化患者的研究转诊进行肝移植.
- 使用身体质量指数 (BMI),中臂周长 (MAC),三肌皮折厚 (TSF),中臂肌周长 (MAMC),手握力 (HGS) 和主观总体评估 (SGA) 来评估营养状况.
- 营养参数与疾病严重程度 (CTP和MELD Na分数) 和死亡率的相关性.
主要成果:
- 营养不良的高患病率:SGA为58%,BMI为12%,MAC为91%,HGS为94%.
- 营养不良指标 (低MAC,SGA) 与晚期肝硬化 (CTP类B/C) 和较高的MELD Na得分有显著的相关性.
- 低MAC和SGA得分与死亡率增加有关.
结论:
- 主观全球评估 (SGA) 是慢性肝病中营养不良的可靠预测指标.
- 早期识别和管理营养不良对于改善患者的治疗结果和潜在地减少肝移植候选人的死亡率至关重要.
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