在美国引起内源性内炎的传染病原体的区域变异:国家数据库分析
Owais M Aftab1, Anup Dupaguntla1, Hamza Khan1
1Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, New Jersey.
Ophthalmology. Retina
|March 16, 2024
概括
在美国各地观察到导致传染性内源性内耳炎 (EE) 的微生物的区域差异. 对甲基西林敏感的金黄色葡萄球菌 (MSSA) 是最常见的原因,但其他微生物的比例因地区而异.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 感染性内源性内眼炎 (EE) 是一种严重的眼内感染.
- 了解致病微生物的区域差异对于有针对性的治疗和预防策略至关重要.
研究的目的:
- 描述在美国内负责传染性内源性内耳炎 (EE) 的微生物的区域变异.
- 分析美国不同地区的人口因素,并发症,微生物概况,死亡率和手术干预.
主要方法:
- 国家住院患者样本数据库 (2002-2014) 的回顾性分析.
- 使用国际疾病分类9号码识别EE病例.
- 根据美国地区 (东北,南部,西部,中西部) 的病例分层.
- 统计分析包括千平方和多变量后勤回归来评估区域差异.
主要成果:
- 总共有10,912个EE案例被分析.
- 在患者人口统计,致病微生物,并发病,死亡率和手术干预方面发现了显著的区域差异.
- 对甲素敏感的金黄色葡萄球菌 (MSSA) 是所有地区最常见的病原体,尽管其比例没有显著变化.
- 在其他传染性微生物的比例 (P < 0.001) 和玻璃切除率 (P = 0.04) 中观察到显著的区域差异.
结论:
- 导致内源性内耳炎 (EE) 的传染性微生物在美国存在区域差异.
- 需要进一步的研究,以了解这些观察到的区域差异的根本原因.
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