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Published on: April 7, 2023

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在克罗恩氏病中,阿巴达西丁尼 (Upadacitinib) 实现了临床和内镜的结果,而不考虑先前的生物暴露

Laurent Peyrin-Biroulet1, Remo Panaccione2, Edouard Louis3

  • 1Department of Gastroenterology, Nancy University Hospital, Vandœuvre-lès-Nancy, France; INSERM, NGERE, University of Lorraine, Nancy, France; INFINY Institute, Nancy University Hospital, Vandœuvre-lès-Nancy, France; FHU-CURE, Nancy University Hospital, Vandœuvre-lès-Nancy, France; Groupe Hospitalier Privé Ambroise Paré - Hartmann, Paris IBD Center, Neuilly-sur-Seine, France.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
|March 16, 2024
PubMed
概括

与安慰剂相比,upadacitinib在中度至重度克罗恩病患者中显示出优异的临床缓解和内镜反应率. 无论先前的生物失效,都观察到有效性,在接受upadacitinib的患者中,有显著的改善.

关键词:
生物学上的失败生物学上的天真.克罗恩氏病是什么?作为一个JAK抑制剂.在Upadacitinib上使用.

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