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Updated: Jun 30, 2025

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治疗向努迪克斯酸酶1会产生MYC驱动的代谢脆弱性

Minhui Ye1,2, Yingzhe Fang1,2, Lu Chen2

  • 1Department of Urology, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.

Nature communications
|March 17, 2024
PubMed
概括

癌细胞重新连接新陈代谢以生长,增加活性氧物种 (ROS). 针对MYC驱动的酶NUDT1,破坏了这种平衡,提供了一种新的癌症治疗策略.

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