基于正念的减轻压力,以治疗艾滋病毒相关神经认知障碍的老年患者的症状
Judith T Moskowitz1,2,3, Brijesh Sharma4,5, Shireen Javandel4
1Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Judith.moskowitz@northwestern.edu.
AIDS and behavior
|March 17, 2024
概括
基于正念的压力减轻 (MBSR) 改善了艾滋病毒相关的神经认知障碍 (HAND) 的老年人抑郁和生活质量. 对抑郁症的好处没有持续,但生活质量的改善仍然存在. 认知功能没有改变.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 感染艾滋病毒的老年人群容易受到艾滋病毒相关的神经认知障碍 (HAND) 症状的影响.
- 基于正念的压力减轻 (MBSR) 对艾滋病毒感染的年轻人有好处.
- 在患有HAND的老年人中,MBSR的疗效仍未得到充分研究.
研究的目的:
- 评估MBSR对艾滋病毒和认知障碍的老年人 (55岁以上) 的心理和认知结果的影响.
- 将MBSR干预与等待名单对照组进行比较.
主要方法:
- 180名55岁以上的艾滋病毒感染者和认知障碍患者被随机分配到为期8周的MBSR或等候名单对照组.
- 心理 (压力,焦虑,抑郁,QOL) 和认知指标在基线,8周和16周被评估.
- 用治疗意向分析来比较不同组的结果.
主要成果:
- 与对照组相比,MBSR组从基线到8周的抑郁症状显著改善,尽管这在16周没有持续.
- 与等候名单对照组相比,MBSR组的感知生活质量 (QOL) 从基线到16周显著改善.
- 在MBSR和对照组之间没有观察到认知表现的显著差异.
结论:
- MBSR显示有潜力减少抑郁症和改善老年人的生活质量.
- 需要进一步的研究,以确定维持MBSR对抑郁症和质量生活的积极影响的策略.
- 在这种人群中,MBSR可能是管理症状负担的有价值的辅助工具.
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