在患有性结肠炎的儿童中使用肠道超声波测量肠壁厚度的单次测量
Masano Otani1,2, Takeru Okuhira1,2, Atsushi Yoden2,3
1Department of Pediatrics, Osaka Saiseikai Suita Hospital, Suita, Osaka, Japan.
通过肠道超声波测量肠壁厚度 (BWT) 在评估性结肠炎 (UC) 儿童中中度性结肠炎时,比性calprotectin (FC) 更有效. 这种非侵入性方法有助于管理儿科UC患者.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 炎症性肠道疾病研究研究
- 诊断成像技术 诊断成像技术
背景情况:
- 内镜监测对于性结肠炎 (UC) 是至关重要的,但具有侵入性,特别是对于儿科患者.
- 像肠道超声波 (肠壁厚度 - BWT) 和便calprotectin (FC) 这样的非侵入性方法是有价值的替代方案.
研究的目的:
- 为了比较BWT和FC在评估儿科UC患者疾病活动中的疗效.
- 为了确定BWT是否可以作为中度结肠炎症的可靠的非侵入性标志物.
主要方法:
- 在儿科UC患者的BWT (mBWT,sBWT,saBWT) 和FC水平的回顾性分析.
- BWT和FC测量与由结肠镜检查确定的梅奥内镜分值 (MES) 的相关性.
主要成果:
- 在轻度 (MES 0-1) 和中度 (MES 2) 炎症之间,BWT和FC水平有显著差异.
- 调整后的BWT总和 (saBWT) 在检测中度炎症 (MES 2) 中显示出比FC更高的灵敏度和准确性.
- 在BWT测量和MES 2测量之间观察到很高的一致性 (89.4%).
结论:
- 肠壁厚度 (BWT),特别是saBWT,是与FC相比,在儿科UC中中度性结肠炎症的优越非侵入性指标.
- 肠道超声波为小儿UC患者的治疗提供了一种不那么侵入性的方法.
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